R&D
German
Desifine Laboratory leads cosmetic R&D with 50 years of Sino-German formula expertise, merging German precision with global innovation. Its German Academy of Sciences-certified formulations embody German rigor, ensuring unmatched efficacy.Backed by 42 SCI papers, 20,000+ formulas, 67 patents, the lab thrives on science.
Its expert team amplifies this: Dr. Rolf (ex-Elizabeth Arden, Henkel) brings 50 years of German formulation insights to industry classics; Academician Wei Kun (European Academy of Natural Sciences) revolutionized extraction (90+ patents); Yuan Jie set TCM safety standards; Dr. Zou Chao advanced skin repair (1,000+ cited papers).
German formula excellence drives Desifine’s innovation, redefining cosmetic science.

ROLF.LENTFER
DESFINE CHIEF ENGINEER
Founder of the basic formula of Desifine
Ph.D. in Chemical Analysis, University of Hamburg, Germany
Former Chief Engineer of Henkel Group China
Former Technical Director and Production Director of three factories of Henkel Group in China
PERSONAL EXPERIENCE
2006 – Present Chief Engineer of Desifine, responsible for the research, development and guidance of basic cosmetic formulas, with a focus on formula R&D in line with German systems
2003 – 2006 Served as Deputy Chief Engineer at the headquarters of Henkel AG & Co. KGaA, Germany, until retirement in 2006
1995 – 2003 Assigned to China, serving as Production and Technical Director of the Cosmetics Division of Henkel China. In charge of the R&D and production of Henkel’s brands including Fa, Komol, Schwarzkopf, Haier Mian (Baby Face) and Fengcai
1982 – 1995 Joined the headquarters of Henkel AG & Co. KGaA (a Fortune Global 500 company) as a Senior Technical Coordinator, with business visits to 65 countries
1978 – 1982 Served as Technical Director at Boerlind Cosmetics GmbH, Germany
1972 – 1978 Worked as Production Supervisor at the German subsidiary of Elizabeth Arden

Dr. Rolf and engineers are in the Foshan laboratory. Rolf has always maintained an international perspective, keeping abreast of cutting-edge international information and technologies, and timely delivering such information and technologies to the work team of DESIFINE, providing real-time guidance and solving challenges and key points in practical operations.

In addition to conducting research and development, Dr. Rolf also visits universities or research institutes abroad to keep abreast of cutting-edge international information and advanced technologies in a timely manner. He promptly delivers such information and technologies to the work assistant team of DESIFINE.

Under the leadership of Rolf, DESIFINE has successively developed tens of thousands of formulated products, including hair care, facial skincare, and body care, etc. Through Rolf's meticulous guidance and the continuous efforts of the team, DESIFINE has obtained two national invention patents, three patents, and the certification of a national high-tech enterprise.

Wei Kun
Technical Chief Advisor of DESIFINE
- Professor, Postdoctoral Fellowat the School of Bioscience and Bioengineering, South China University of Technology;
- D. Supervisor, Head of the Biomedical Specialty
- Academician of the European Academy of Natural Sciences
- Leading Figure of the 5th World Integrated Medicine Experts
- Standing Committee Member of the Nanobiotechnology of the China Association for Medical Biotechnology;
- “Expert in Traditional Chinese Medicine Health Services” of the China Medical Education Association
- Vice Chairman of the Guangdong Foundation for the Development of Traditional Chinese Medicine.

Yuan Jie
Director of Global Formula R&D Center of DESIFINE
- Expert of Major New Drug Creation under the Ministry of Science and Technology of China
- Cosmetics Review Expert of the National Medical Products Administration
- Talent Introduced under Guangdong’s “Yangfan Program”
- Director of Guangdong Key Laboratory of New Traditional Chinese Medicine R&D
- Professor and Medical Doctor of Guangzhou University of Chinese Medicine
- Director of “New Drug Lead Compound Laboratory” of Guangzhou University of Chinese Medicine

Chen Jianying
Chief Engineer of the R&D Center
- D. in Materials Science, South China University of Technology
- Current research focus: Development of high-efficiency anti-aging research based on DNA
- Author of 7 high-impact SCI papers

Zeng Jihui
Chief Engineer of the Technology Department
- Graduate in Fine Chemicals, University of Lyon 1, France
- Former Senior Biological R&D Project Engineer in a Fortune Global 500 overseas enterprise
- Once participated in research on special projects related to biomedical peptides in France
- With 12 years of rich experience in formula R&D in the chemical industry

Zou Chao
Chief Scientist of the DESIFINE Raw Material Research Institute
- D. in Molecular Biology, Tottori University / National Institute of Genetics, Japan
- Postdoctoral Researcher at Queen’s Medical Centre, University of Nottingham, UK
- Postdoctoral Researcher at the School of Medicine, University of Virginia, USA
- Senior Researcher at the R&D Center (USA) of Sanofi-Aventis (a Fortune Global 500 pharmaceutical company)
- Technical Director of Easy Bio Inc. (USA)
- Visiting Professor at the Medical Center of New York University
- Included in Who’s Who in Science and Engineering(USA) and Who’s Who in the World (USA)
- Listed in Yearbook of Excellent Chinese Invention Patentsin 2012

Chen Zhongmiao
Chief Engineer of Body – project in Technical Department
- Bachelor of Fine Chemicals, South China University of Technology
- With more than 20 – year experience in cosmetics R&D
INNOVATION



Elastin, key to maintaining tissue elasticity and widely found in the skin, arteries and lungs, works with collagen in the skin to provide firmness and elasticity—its elasticity is a thousand times that of collagen, vital for delaying skin aging. However, natural elastin’s poor water solubility has long been a technical hurdle. Through in-depth research on its molecular structure, Desifine and Dr. Zou’s team adjusted the hydrophobic and hydrophilic domains of original elastin using genetic and protein engineering, achieving water solubility while preserving its core structure.
TECHNICAL ADVANTAGES
Active Ingredients
By utilizing the growth characteristics of cells and biological catalytic systems, reacting with organic substrates, the target active products are directionally obtained, effectively preserving the active substances in plant raw materials.
Transdermal Absorption
Active ingredients wrapped in liposomes can perfectly fuse with cell membranes, achieving the effect of penetrating cell membranes, improving absorption rate, and making the components act more effectively for a longer time.
Signal Regulation
Open up the cell information pathway, receive accurate signal commands into the cell nucleus, stimulate cells to produce endogenous substances, and prolong cell lifespan.
Precise Targeting
Using biomedical technology, it precisely acts on sub-health and aging points according to cellular needs, achieving sustained release.
Non-emulsification technology
By abandoning traditional emulsifiers and leveraging new technologies, this approach achieves precise combination of oil and water phases, forming a basic emulsion system that efficiently penetrates the stratum corneum. It simplifies the production process while reducing chemical additives, balancing repair efficacy and mildness.
CERTIFICATION


GMPC

ISO22716

Firming Massage Cream Patent

Nanoparticle Preparation Technology Patent

Patent for Lipid-Lowering and Weight-Loss Massage Cream

Plant Extract Composition Patent

Water Treatment Equipment Patent

Absorption-Promoting Preparation Patent

Anti-aging Composition Patent

Repairing Mask Essence Patent
INGREDIENTS WE DO NOT USE IN OUR PRODUCTS
Desifine products contain none of the following ingredients. Though trace amounts might occasionally be present due to factors like water sources, natural environmental exposure, or technically unavoidable aspects of the manufacturing process, we guarantee product safety by adhering to the stringent regulatory requirements of global markets
- 1,4-Dioxane
- Acetaldehyde
- Acetonitrile
- Acrylamide
- Benzene
- BHA (Butylated hydroxyanisole)
- Bisphenol A
- Boric acid
- Butoxyethanol
- D4 (Cyclotetrasiloxane)
- Dichloroethane
- Diethanolamine (DEA) and diethanolamine (DEA) Complexes
- Formaldehyde
- Heavy metals (Lead, Arsenic, Mercury, Cadmium, Antimon, Nickel)
- Hexachlorophene
- Hydroquinone
- Methanol
- Methylene chloride
- PCBs (Polychrorinated biphenyls)
- Phthalates
- Plastic microbeads (Rinse off products)
- PVC
- Toluene