R&D

years of Sino-German formula research and accumulation
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SCI papers
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SCI papers
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domestic and foreign invention patents
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German

Formula certification from the German Academy of Sciences

Desifine Laboratory leads cosmetic R&D with 50 years of Sino-German formula expertise, merging German precision with global innovation. Its German Academy of Sciences-certified formulations embody German rigor, ensuring unmatched efficacy.Backed by 42 SCI papers, 20,000+ formulas, 67 patents, the lab thrives on science.

Its expert team amplifies this: Dr. Rolf (ex-Elizabeth Arden, Henkel) brings 50 years of German formulation insights to industry classics; Academician Wei Kun (European Academy of Natural Sciences) revolutionized extraction (90+ patents); Yuan Jie set TCM safety standards; Dr. Zou Chao advanced skin repair (1,000+ cited papers).

German formula excellence drives Desifine’s innovation, redefining cosmetic science.

ROLF.LENTFER

DESFINE CHIEF ENGINEER

Founder of the basic formula of Desifine
Ph.D. in Chemical Analysis, University of Hamburg, Germany
Former Chief Engineer of Henkel Group China
Former Technical Director and Production Director of three factories of Henkel Group in China

PERSONAL EXPERIENCE

  • 2006 – Present Chief Engineer of Desifine, responsible for the research, development and guidance of basic cosmetic formulas, with a focus on formula R&D in line with German systems
 
 
  • 2003 – 2006 Served as Deputy Chief Engineer at the headquarters of Henkel AG & Co. KGaA, Germany, until retirement in 2006
 
 
  • 1995 – 2003 Assigned to China, serving as Production and Technical Director of the Cosmetics Division of Henkel China. In charge of the R&D and production of Henkel’s brands including Fa, Komol, Schwarzkopf, Haier Mian (Baby Face) and Fengcai
 
 
  • 1982 – 1995 Joined the headquarters of Henkel AG & Co. KGaA (a Fortune Global 500 company) as a Senior Technical Coordinator, with business visits to 65 countries
 
 
  • 1978 – 1982 Served as Technical Director at Boerlind Cosmetics GmbH, Germany
 
 
  • 1972 – 1978 Worked as Production Supervisor at the German subsidiary of Elizabeth Arden
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Dr. Rolf and engineers are in the Foshan laboratory. Rolf has always maintained an international perspective, keeping abreast of cutting-edge international information and technologies, and timely delivering such information and technologies to the work team of DESIFINE, providing real-time guidance and solving challenges and key points in practical operations.

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In addition to conducting research and development, Dr. Rolf also visits universities or research institutes abroad to keep abreast of cutting-edge international information and advanced technologies in a timely manner. He promptly delivers such information and technologies to the work assistant team of DESIFINE.

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Under the leadership of Rolf, DESIFINE has successively developed tens of thousands of formulated products, including hair care, facial skincare, and body care, etc. Through Rolf's meticulous guidance and the continuous efforts of the team, DESIFINE has obtained two national invention patents, three patents, and the certification of a national high-tech enterprise.

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Wei Kun

Technical Chief Advisor of DESIFINE

  • Professor, Postdoctoral Fellowat the School of Bioscience and Bioengineering, South China University of Technology;
  • D. Supervisor, Head of the Biomedical Specialty
  • Academician of the European Academy of Natural Sciences
  • Leading Figure of the 5th World Integrated Medicine Experts
  • Standing Committee Member of the Nanobiotechnology of the China Association for Medical Biotechnology;
  • “Expert in Traditional Chinese Medicine Health Services” of the China Medical Education Association
  • Vice Chairman of the Guangdong Foundation for the Development of Traditional Chinese Medicine.
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Yuan Jie

Director of Global Formula R&D Center of DESIFINE

  • Expert of Major New Drug Creation under the Ministry of Science and Technology of China
  • Cosmetics Review Expert of the National Medical Products Administration
  • Talent Introduced under Guangdong’s “Yangfan Program”
  • Director of Guangdong Key Laboratory of New Traditional Chinese Medicine R&D
  • Professor and Medical Doctor of Guangzhou University of Chinese Medicine
  • Director of “New Drug Lead Compound Laboratory” of Guangzhou University of Chinese Medicine
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Chen Jianying

Chief Engineer of the R&D Center

  • D. in Materials Science, South China University of Technology
  • Current research focus: Development of high-efficiency anti-aging research based on DNA
  • Author of 7 high-impact SCI papers
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Zeng Jihui

Chief Engineer of the Technology Department

  • Graduate in Fine Chemicals, University of Lyon 1, France
  • Former Senior Biological R&D Project Engineer in a Fortune Global 500 overseas enterprise
  • Once participated in research on special projects related to biomedical peptides in France
  • With 12 years of rich experience in formula R&D in the chemical industry
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Zou Chao

Chief Scientist of the DESIFINE Raw Material Research Institute

  • D. in Molecular Biology, Tottori University / National Institute of Genetics, Japan
  • Postdoctoral Researcher at Queen’s Medical Centre, University of Nottingham, UK
  • Postdoctoral Researcher at the School of Medicine, University of Virginia, USA
  • Senior Researcher at the R&D Center (USA) of Sanofi-Aventis (a Fortune Global 500 pharmaceutical company)
  • Technical Director of Easy Bio Inc. (USA)
  • Visiting Professor at the Medical Center of New York University
  • Included in Who’s Who in Science and Engineering(USA) and Who’s Who in the World (USA)
  • Listed in Yearbook of Excellent Chinese Invention Patentsin 2012
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Chen Zhongmiao

Chief Engineer of Body – project in Technical Department

  • Bachelor of Fine Chemicals, South China University of Technology
  • With more than 20 – year experience in cosmetics R&D

INNOVATION

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Caffeine boosts metabolism and local microcirculation,but it’s hard to dissolve in water or alcohol. That’s why adding it to shampoos and creams has long been tricky—most products only get to 0.8%. Dr. ROLF’s Desifine Lab team broke this limit to 1.4%! Our shampoo essence, with caffeine and Platycladus orientalis, reduces breakage and hair loss, winning wide favor.
 
Unfrozen technology Water freezes solid at 0°C, yet the hair oil styling and care products developed by the Desifine team remain fully usable even at -22°C. Tests show that some similar products on the market start to freeze at just -1°C, while Our hair oil series stays in normal condition at -22°C, reaching an internationally leading standard.
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Elastin, key to maintaining tissue elasticity and widely found in the skin, arteries and lungs, works with collagen in the skin to provide firmness and elasticity—its elasticity is a thousand times that of collagen, vital for delaying skin aging. However, natural elastin’s poor water solubility has long been a technical hurdle. Through in-depth research on its molecular structure, Desifine and Dr. Zou’s team adjusted the hydrophobic and hydrophilic domains of original elastin using genetic and protein engineering, achieving water solubility while preserving its core structure.

TECHNICAL ADVANTAGES

Active Ingredients

By utilizing the growth characteristics of cells and biological catalytic systems, reacting with organic substrates, the target active products are directionally obtained, effectively preserving the active substances in plant raw materials.

Transdermal Absorption

Active ingredients wrapped in liposomes can perfectly fuse with cell membranes, achieving the effect of penetrating cell membranes, improving absorption rate, and making the components act more effectively for a longer time.

Signal Regulation

Open up the cell information pathway, receive accurate signal commands into the cell nucleus, stimulate cells to produce endogenous substances, and prolong cell lifespan.

Precise Targeting

Using biomedical technology, it precisely acts on sub-health and aging points according to cellular needs, achieving sustained release.

Non-emulsification technology

By abandoning traditional emulsifiers and leveraging new technologies, this approach achieves precise combination of oil and water phases, forming a basic emulsion system that efficiently penetrates the stratum corneum. It simplifies the production process while reducing chemical additives, balancing repair efficacy and mildness.

CERTIFICATION

2025-07-15_115555_039
GMPC
GMPC
ISO22716
ISO22716
Firming Massage Cream Patent
Firming Massage Cream Patent
Nanoparticle Preparation Technology Patent
Nanoparticle Preparation Technology Patent
Patent for Lipid-Lowering and Weight-Loss Massage Cream
Patent for Lipid-Lowering and Weight-Loss Massage Cream
Plant Extract Composition Patent
Plant Extract Composition Patent
Water Treatment Equipment Patent
Water Treatment Equipment Patent
Absorption-Promoting Preparation Patent
Absorption-Promoting Preparation Patent
Anti-aging Composition Patent
Anti-aging Composition Patent
Repairing Mask Essence Patent
Repairing Mask Essence Patent

INGREDIENTS WE DO NOT USE IN OUR PRODUCTS

Desifine products contain none of the following ingredients. Though trace amounts might occasionally be present due to factors like water sources, natural environmental exposure, or technically unavoidable aspects of the manufacturing process, we guarantee product safety by adhering to the stringent regulatory requirements of global markets

We never stop researching and innovating—all to safeguard your beauty!